Document Type : Original Article
Authors
1
Student Research Committee, Kerman University of Medical Sciences, Kerman, Iran
2
Social Determinants of Health Research Center, Institute for Futures Studies in Health, Kerman University of Medical Sciences, Kerman, Iran
3
Kerman Neuroscience Research Center, Institute of Neuropharmacology, Kerman University of Medical Sciences, Kerman, Iran
10.34172/JHAD.92363
Abstract
Background: Potentially inappropriate medications (PIMs) should not be prescribed to the elderly due to low effectiveness and
adverse drug reactions. This study was conducted to determine the frequency of PIMs in the elderly admitted to educational
hospitals in Kerman, in 2023.
Methods: This cross-sectional study was conducted on 1500 elderly patients hospitalized in educational hospitals. The data
collection forms were completed according to the health information system (HIS) of the hospital, which includes the patient’s
age and gender, drug information, and the name of the hospital and ward. PIMs prescriptions were assessed according to Zhan’s
criteria. Statistical analyses were performed using SPSS version 20.0. The results were presented as mean ± standard deviation (SD)
and frequencies (percents).
Results: Nearly 17.8% (n = 267) of patients were treated with at least one PIMs included in the Zhan criteria. Among 331 PIMs used
for patients, 43.5% (n = 144), 23.3% (n = 77), and 33.2% (n = 110) of drugs were classified as always avoid, rarely appropriate, and
some indication, respectively. Sedative-hypnotics, opioids, and antihistamines were the most prevalent PIMs with 29.5% (n = 98),
25.4% (n = 84), and 23.3% (n = 77) frequency. Approximately 71.4% (n = 10) of patients who were admitted to the Oncology
ward, and 38.9% (n = 33) of patients who were admitted to the Critical Care Unit were treated with at least one PIMs.
Conclusion: Today PIMs are a problem for elderly patients. Paying attention to PIMS in oncology, and critical care unit wards is
important. More attention should be paid to sedative-hypnotics, opioids, and antihistamines as the most frequently prescribed PIMs
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